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Elderly individuals (aged 65 many years or older) can have elevated sensitivity to NORCO. On the whole, use caution when selecting a dosage for an aged patient, normally starting off at the very low stop with the dosing range, reflecting the bigger frequency of diminished hepatic, renal, or cardiac purpose and of concomitant illness or other drug therapy.

Use other supportive actions (like oxygen and vasopressors) inside the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias would require State-of-the-art everyday living-assist tactics.

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There were infrequent reviews of daily life-threatening anaphylaxis necessitating emergency medical focus. Instruct clients to discontinue NORCO right away and find medical treatment when they experience these signs and symptoms. Never prescribe NORCO Tablets for people with acetaminophen allergy [see Affected individual Information and facts].

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Because the duration of opioid reversal is expected for being below the length of action of NORCO in NORCO Tablets, cautiously keep track of the patient till spontaneous respiration is reliably re-founded.

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If concomitant use is warranted, follow clients for signs of diminished diuresis and/or effects on hypertension and raise the dosage in the diuretic as needed.

Doctors from time to time prescribe opioid pain relievers for their clients that are in pain. Although these medication can provide much-required relief, they also have the prospective for misuse and addiction.

Tell female sufferers of reproductive probable that extended utilization of NORCO through pregnancy may result in neonatal opioid withdrawal syndrome, which can be daily life-threatening if not regarded and addressed [see WARNINGS, Safeguards; Pregnancy].

The concomitant usage of anticholinergic prescription drugs may perhaps improve danger of urinary retention and/or serious constipation, which can bring about paralytic ileus.

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